Stopping lithium

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Stopping lithium
  • 6 months treatment is considered an adequate trial to establish effectiveness.
  • Discontinuation should be planned except in cases of toxicity. Abrupt withdrawal increases the risk of relapse.
  • Reduce the dose gradually over at least 4 weeks, preferably up to 3 months.
  • Continue to monitor lithium levels whilst reducing the dose.
Editorial Information

Last reviewed: 03 September 2019

Next review: 12 July 2021

Author(s): PMG-MH

Version: 1

Approved By: PMG-MH

Reviewer Name(s): Andrew Walker, Suzanne Burke